Circulatory corticotropin-releasing hormone mRNA concentrations are increased in women with preterm delivery but not in those who respond to tocolytic treatment.

نویسندگان

  • Xiao Yan Zhong
  • Wolfgang Holzgreve
  • Irene Hoesli
  • Sinuhe Hahn
چکیده

Concentrations Are Increased in Women with Preterm Delivery But Not in Those Who Respond to Tocolytic Treatment, Xiao Yan Zhong, Wolfgang Holzgreve, Irene Hoesli, and Sinuhe Hahn ( Laboratory for Prenatal Medicine, University Women’s Hospital, and Department of Research, University Hospital Basel, Basel, Switzerland; 2 University Women’s Hospital, University Hospital Basel, Basel, Switzerland; * address correspondence to this author at: Laboratory for Prenatal Medicine, University Women’s Hospital, University Hospital Basel, Spitalstrasse 21, CH-4031 Basel, Switzerland; fax 41-61-2659399, e-mail [email protected])

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Abnormal progesterone and corticotropin releasing hormone levels are associated with preterm labour.

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 Background & Aims: Preterm labor is one of the most important obstetrics problems that is the most common cause of neonatal mortality and finding an effective treatment with least adverse effects is always under serious concern. The purpose of the present study is to compare the efficacy of two tocolytic agents of nifedipin and indomethacin for treatment of preterm labor and their complication...

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Low levels of corticotropin-releasing hormone during early pregnancy are associated with precocious maturation of the human fetus.

Elevation in placental corticotropin-releasing hormone (pCRH) during the last trimester of pregnancy has been associated with an increased risk for preterm delivery. Less is known about the consequences for the human fetus exposed to high levels of pCRH early in pregnancy. pCRH levels were measured in 138 pregnant women at least once at 15, 20 and 25 weeks of gestation. At 25 weeks of gestation...

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نیفدیپین و ایندومتاسین جهت درمان زایمان زودرس

Introduction: This study aimed to compare the efficacy of 2 tocolytic agents of nifedipin and indomethacin for treatment of preterm labor and their complications. Methods: The study was conducted as a randomized clinical trial on 79 pregnant women who were admitted for labor pain at 26-33 weeks of gestation. In the nifidipin group (40 cases), oral nifedipin and in the indomethacin group(39 cas...

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عنوان ژورنال:
  • Clinical chemistry

دوره 51 3  شماره 

صفحات  -

تاریخ انتشار 2005